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  • The prior article with this series presented the traditional treatments for opiates addiction. Suboxone allows a whole new approach.

    Using two separate drugs to shed weight can be very effective there are combinations before the FDA now awaiting approval. When dealing with weight loss and the those who go through it one should err on the side of caution and permit the FDA do its job and demand some research be done so the public recognizes the side effects and dangers of the medications before we bring them. Keep in mind that drug companies have been in business to generate income and that they would say anything to keep people on the medications.

    Researchers found that participants using this drug for the year, dropped excess weight within a month and have kept the extra weight off through the 56 weeks from the study. Contrave is a combination of the drugs naltrexone and bupropion, which seems to reflect a fresh trend of weight-loss drugs which are made up of multiple active ingredient, which can make them more effective and safer.

    Combo-pilling is the newest fad or better yet the newest to come under scrutiny and for that reason it is just more publicly known although in the past, comb-pilling for losing weight has been around since the eighties. The biggest reason that employing a combination of pills is starting to become popular is the fact that at the time of right now there are no long term prescription diet pills that have been authorized by the FDA apart from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications although some people might of the combinations are already rejected or have yet to be authorized by the FDA.

    Seizures can be a side effect with Contrave and shouldn't be taken in individuals with seizure disorders. The drug could also raise blood pressure level and heartbeat, and must not be used in people who have a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with the drug.

    The FDA also warned that Contrave can raise hypertension and heartrate and must 't be used in patients with uncontrolled high hypertension, along with by anyone with heart-related and cerebrovascular (circulation dysfunction impacting your brain) disease. Patients having a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes which has a boxed warning to alert health care professionals and patients on the increased likelihood of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for smoking cessation.

    Suboxone contains two drugs; buprenorphine and naloxone. The naloxone is irrelevant if the addict uses the medication properly, but if the tablet is dissolved in water and injected the naloxone may cause instant withdrawal. When suboxone can be used correctly, the naloxone is destroyed inside liver after that uptake in the intestines and contains no therapeutic effect. Buprenorphine will be the active substance; it can be absorbed under the tongue (and throughout the mouth) but destroyed through the liver if swallowed. There is a formulation of buprenorphine without naloxone called subutex; I purchased this formulation in the event the patient has apparent problems from naloxone, including headaches after dosing with suboxone. I also have treated addicts who've had gastric bypass, the location where the first area of the intestine is bypassed and the stomach contents empty in to a more distal section of the small intestine. In such cases the naloxone escapes ?first pass metabolism', the procedure with normal anatomy in which the drug is taken up from the duodenum and transferred directly to the liver from the portal vein, where it really is quickly and completely destroyed. After gastric bypass naloxone can be taken on by areas of the intestine which are not served through the portal system, causing blood levels of naloxone sufficient to cause brief, relatively mild withdrawal symptoms.

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